Being HIV positive and staying on antiretroviral therapy in Africa

An international team of researchers have carried out a review of the evidence examining what influences people who are HIV positive to go to health services and then stay on antiretroviral drugs in Africa. In a paper published in the Journal PLOS One the team, led by LSTM’s Professor Paul Garner, used advanced methods of…

Human rights ‘core guiding principle’ of new HIV, AIDS law

MANILA, Philippines – Lawmakers hailed the passage of the new law strengthening the country’s comprehensive policy on the Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS), saying human rights is one of its central principles. On Wednesday, January 9, Dinagat Islands Representative Kaka Bag-ao and Akbayan Representative Tom Villarin – two of the…

The opioid crisis: What we should learn from the AIDS epidemic

There are important lessons to be learned from the successes and failures of the AIDS response that could inform our response to the opioid epidemic, according to a new paper by researchers at the Columbia University Mailman School of Public Health. Decades of HIV research have demonstrated that the existence of an effective biomedical treatment…

HIV-positive children dream big

“We are together in this,” Reverend Colonel Selotlegeng Colane, from the Northern Cape faith based sector, told a group of children born with HIV at a three-day educational camp in Kimberley. Big dreams for the future The camp, which was facilitated by the Department of Social Development, brought 52 children born with HIV together to…

Cell size and cell-cycle states play key decision-making role in HIV

The life-saving drugs don’t cure HIV, though, because when the virus infects the body, it insidiously targets the very cells required to trigger the body’s immune response to any infection. Specifically, HIV invades CD4 T-cells — a type of white blood cell — making copies of itself and taking over the CD4 host cell’s DNA….

AIDS: An approach for targeting HIV reservoirs

Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified the characteristics of CD4 T lymphocytes that are preferentially infected by the virus — it is their metabolic (or energy-producing) activity that enables the virus…

HIV vaccine protects non-human primates from infection

For more than 20 years, scientists at Scripps Research have chipped away at the challenges of designing an HIV vaccine. Now new research, published in Immunity, shows that their experimental vaccine strategy works in non-human primates. The new study shows that rhesus macaque monkeys can be prompted to produce neutralizing antibodies against one strain of…

Unique immune cell likely drives chronic inflammation

Even with effective viral control, HIV-infected individuals are at a higher risk for morbidities associated with older age than the general population. Unfortunately, the cell subsets driving inflammation in HIV infection and with normal aging are not yet understood. Also, whether antiretroviral therapy (ART) suppressed HIV infection causes premature induction of the inflammatory events found…

5 ridiculous things some people still believe about HIV/Aids

It’s time to shine the light on some of the ridiculous and far-fetched perceptions about HIV that people still have.HIV has become completely manageable, but it is surprising how many people still believe some of the misconceptions about the condition.The theme of 2018 is “Know your status”, which emphasises the importance of getting tested. Here…

A topic of heated debate: Should HIV testing be compulsory?

A matter of public interest or an infringement of human rights? We take a look at the debate around compulsory HIV testing. According to UNAIDS, 36.9 million people around the world are living with HIV. South Africa currently has the largest HIV epidemic in the world, with 7.2 million of its citizens affected by the…