Combining antibiotics changes their effectiveness

In the first large-scale screening of its kind, scientists profiled almost 3000 drug combinations on three different disease-causing bacteria. The research was led by EMBL group leader Nassos Typas. Overuse and misuse of antibiotics has led to widespread antibiotic resistance. Specific combinations of drugs can help in fighting multi-drug resistant bacterial infections, but they are…

Lung Cancer Biomarkers: Implications from Proteomics

Quantitative Proteomics in Lung Cancer Biomarkers Discovery: Proteins are involved in all biological processes which can be regarded as the final stage of biological information from genome. Proteomics is extremely dynamic and complex due to the continuous response to the change of environment, drug treatment, and post-translational modification. Large-scale and systematic analysis of proteins is…

PEGylation, New Service for Improving Pharmacological Properties of Protein Therapeutics

According to the researchers synthetic polymer PEG modification and bioconjugation services on peptide/proteins, oligonucleotides, antibodies, lectins, enzymes, toxins, drugs or other small molecules for a variety of applications. Types and Applications Common limits for therapeutic application of peptides and proteins are their chemical instability, their short circulation time in blood and their tendency to promote…