National Institutes of Health supports novel drug discovery research

Approximately $1.7 million in new funding from the National Institutes of Health will enable a multidisciplinary team of University of Illinois at Chicago researchers to build a reference library of bacteria to help scientists quickly identify bacterial strains and analyze their disease-fighting potential. 12th International Conference on Pharmaceutical Chemistry during May 20-21, 2019 at Berlin, Germany.  The conference emphasizes the theme “Exploring the Challenges in…

Robotic System could Reduce the Cost of Drug Discovery

Developing a new drug is expensive and time-consuming. One major challenge is the sheer number of experiments needed to prove a drug is safe. Literally thousands of experiments with each potential treatment represents a huge investment in time and money. Robotic systems might hold the key to reducing development costs and also speeding up the…

Opioid-Induced Constipation: A New Drug to Treat the Side Effects of Opioids

During the 2016 Super Bowl, an advertisement featured a man suffering from opioid-induced constipation. Superficially, the commercial appeared to raise awareness of a distressing condition and suggest a solution to the problem. On a deeper level, it kicked off a discussion on how opioid-induced constipation might be better addressed by first reducing the use of…

Scientists develop first non-antibiotic drug to treat tuberculosis in animals

Scientists at The University of Manchester have developed the first non-antibiotic drug to successfully treat tuberculosis in animals. 12th International Conference on Pharmaceutical Chemistry from May 20-21, 2019 at Berlin, Germany. For more details kindly visit www.meetingsint.com/conferences/pharmachemistry The team hope the compound -developed after 10 years of painstaking research will be trialed on humans within three…

Combining antibiotics changes their effectiveness

In the first large-scale screening of its kind, scientists profiled almost 3000 drug combinations on three different disease-causing bacteria. The research was led by EMBL group leader Nassos Typas. Overuse and misuse of antibiotics has led to widespread antibiotic resistance. Specific combinations of drugs can help in fighting multi-drug resistant bacterial infections, but they are…

Researchers identify new regulator in breast cancer cells

Triple-negative breast cancer is a particularly aggressive form of breast cancer. Here, important receptors are missing, which often serve as targets for treatments. Thus, these tumors are unlikely to respond to current therapies. Researchers from the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena now identified the protein TRPS1, which is commonly…

Metabolomics and Biomarkers for Drug Discovery

Metabolomics is an emerging science involving the study and characterization of metabolites and metabolism in biological systems using an integrated approach which generates unique chemical fingerprints for specific cellular processes. According to the Metabolomics Society, metabolomics is a newly emerging field of “omics” research concerned with the comprehensive characterization of the small molecule metabolites in…

What is the difference between precision medicine and personalized medicine? What about pharmacogenomics?

There is a lot of overlap between the terms “precision medicine” and “personalized medicine.” According to the National Research Council, “personalized medicine” is an older term with a meaning similar to “precision medicine.” However, there was concern that the word “personalized” could be misinterpreted to imply that treatments and preventions are being developed uniquely for…

The Age of Personalized Medicine?

Personalized medicine is the tailoring of medical treatment to the individual characteristics of each patient. The approach relies on scientific breakthroughs in our understanding of how a person’s unique molecular and genetic profile makes them susceptible to certain diseases. This same research is increasing our ability to predict which medical treatments will be safe and…